Nitric oxide ( NO ), produced by the cells lining the blood vessels, helps regulate blood flow and maintain chemical balance in the body. NO production decreases in people with the metabolic Syndrome – symptoms that include insulin resistance, abdominal obesity, abnormal blood fats, high blood pressure, cellular inflammation and blood-clotting abnormalities. NO deficiencies decrease sexual performance, impair vitality and promote coronary artery disease improving exercise and dietary habits are the best ways to promote metabolic health and maximize nitric oxide production. Italian researchers found that arginine supplements improved blood sugar metabolism, insulin sensitivity, nitric oxide secretion and reduced oxidative stress in obese, insulin-resistant type 2 diabetic patients. The supplement’s effect were independent of changes in exercise and diet. Arginine supplements may promote metabolic health. ( American Journal Physiology Endocrinology Metabolism, 291: E906-E912, 2006 )
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